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DNA Structure and Replication: Crash Course Biology #10

41718 ratings | 5159676 views
Hank introduces us to that wondrous molecule deoxyribonucleic acid - also known as DNA - and explains how it replicates itself in our cells. Crash Course Biology is now available on DVD! http://dftba.com/product/1av/CrashCourse-Biology-The-Complete-Series-DVD-Set Like CrashCourse on Facebook: http://www.facebook.com/YouTubeCrashCourse Follow CrashCourse on Twitter: http://www.twitter.com/TheCrashCourse References for this episode can be found in the Google document here: http://dft.ba/-2hCl 1:41 link to Biological Molecules http://www.youtube.com/watch?v=H8WJ2KENlK0 Table of Contents: 1) Nucleic Acids 1:30 2) DNA -A) Polymers 1:53 -B) Three Ingredients 2:12 -C) Base Pairs 3:45 -D) Base Sequences 4:13 3) Pop Quiz 5:07 4) RNA 5:36 -A) Three Differences from DNA 5:43 5) Biolography 6:16 6) Replication 8:49 -A) Helicase and Unzipping 9:22 -B) Leading Strand 9:38 -C) DNA Polymerase 10:08 -D) RNA Primase 10:24 -E) Lagging Strand 10:46 -F) Okazaki Fragments 11:07 -F) DNA Ligase 11:47 DNA, deoxyribonucleic acid, chromosome, nucleic acid, ribonucleic acid, RNA, polymer, nucleotide, double helix, nucleotide base, base pair, base sequence, friedrich miescher, rosalind franklin, replication, helicase, leading strand, lagging strand, rna primase, dna polymerase, okazaki fragment Support CrashCourse on Subbable: http://subbable.com/crashcourse
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Text Comments (4150)
Pam Valti (13 hours ago)
Every time I leave still confused after watching a crash course video and then read the YouTube comments of people saying he made them understand it easily... I start to believe that my brain is just not capable of the amount of intelligence everyone else seems to have *eye twitch*
CaveGame (1 day ago)
Can you plz code sub2me in rinonuclyic acid (unicode)
Victor Rafstedt (2 days ago)
Thank you so much Hank, i got an A+ in my biology exam and this video was key!
Asha Gerbrandt (3 days ago)
who else is here cramming for their science exam which is tomorrow?
Kactus Ricardo (3 days ago)
*Thank you so much for this video!* I have a mini test tomorrow to do with *Structure and Replication of DNA* and this is as close to what my teacher has been teaching in class, than any other resource I could find! I have watched this video a couple of times now and it's not boring at all, in fact *i'm picking up a lot more each time I watch it!* Now, i'm off to find out more about "semi-conservative" as I still have no clue about it, but I think this video has helped me to understand it a little even though it wasnt mentioned haha once again *thank you*
nicole nina chavez (6 days ago)
Why are the rings in the purines both hexagonal? Purine rings are made up of hexa and penta rings,right?
Ricardo (8 days ago)
Michael Truong (9 days ago)
Thank you! Very informative and creative video!
Hannah Foley (9 days ago)
anyone else trying to cram an impossible amount of information into their head the day before an exam?
Ioan Jivan (10 days ago)
so many scientists were crooks
Callum Garland (10 days ago)
Hey Hank, how are you going? I was just curious as to what car you drive? Cheers
Connor P (10 days ago)
What car do you drive Hank?
Courtney Prather (11 days ago)
These videos are so helpful! Much easier to understand than reading a textbook. Thank you!!
ThatOddballAmelia (16 days ago)
cramming for an honors bio final... god help me
TheLamboDude // TLD_HD (16 days ago)
we just watch you in class lol :)
Wanna make one adult joke there lol
Jower (17 days ago)
Richard Rotonde (19 days ago)
you have no life.
maimoona irfan (21 days ago)
I love how he talks about something gross that a scientist did then goes like "it's for science so it's ok" to make it less awkward 😂😂😂😂
Chelsea Hudson (22 days ago)
I shouldn't be paying for a college tuition when Hank (newly) and John have been my prime educators since 5th grade
Bloody Psycho (22 days ago)
And all of this happened by coincidence eh?!!
Sophie S. (22 days ago)
it’s 230 am the exam is in 5 hours and i’ve officially lost all control thank you for this hank bless your soul
Alilikesstuff (22 days ago)
I just took a DNA test about how my body reacts to Cannabis lol really cool to learn more about DNA
Isa Smedberg (23 days ago)
you got me an A on my test thankssss
Matt Norris (25 days ago)
Someone give this man a pore strip
Uvindu Abeysekara (25 days ago)
why did ur mole change sides on ur neck
A V A (1 month ago)
Am I the only one who finds him the least bit attractive? God this sounds weird.
Laia Pedro Roig (1 month ago)
Amazing video! And wonderful and very well deserved tribute to Rosalind
SciStudio (1 month ago)
Thank you so much for being an inspiration for me to start out my own educational science channel! I hope you guys can give me an opportunity by visiting my channel and checking out my science channel and my video on topics such as energy metabolism. Glycolysis, Krebs cycle, gluconeogenesis, glucogen, etc where I explain complex concept in a easy to understand manner and with mnemonics for better memory retention. SciStudio is a YouTube channel that seeks to ignite the passion for science and the wonders of this world with entertaining and easy-to-understand educational videos. We hope to make puzzling science concepts fun, awesome and easy all the way from high school students to the common folks who want to know more about the beauty of science. Do check us out! And once again thank you for being an inspiration for me! 😊
Miranda Klope (1 month ago)
did anyone else feel sexually harassed at 47 seconds? just me okay thanks ;)
Georgeina Samuels (1 month ago)
Your videos are so helpful.. I have an exam in 28 mins and your videos are saving me rn!!
Technolocic (1 month ago)
if you took the lenght of every dna in every cell in everyperson alive tody it would probably be the lenght of the entire universe like 5 times
Sweta Muthusaravanan (1 month ago)
Thankss a lot ....u made me love my exam..ha..ha
Mamata Nanda (1 month ago)
What is helicase??
Alana Graham (1 month ago)
Mamata Nanda all I know is that it’s an enzyme used to break the hydrogen bonds between the bases.
Jettapat Lengsiriwat (1 month ago)
ทำไม 5’ กับ 3’ ถึงเป็นตำแหน่งเดียวกันล่ะครับ
iluvmanga (1 month ago)
The test is in three hours...
Yasmin Rauhen (1 month ago)
Passing bio eAssessement td, watching this thinking it ll help
Mathews Tomat (1 month ago)
Where we dropping bois
Future_ shock (1 month ago)
dude biology is bloddy hard!
Christina Rose (1 month ago)
AP Biology anyone?
Tommy Flynn (1 month ago)
Why would you dislike this
Eumin Shin (1 month ago)
who else is here 5-13-18 stressing the day before the exam?
Gavin Zurmely (1 month ago)
Excuse me Hank, but I am not a human. I am a Neko​ resembling a demonic canine
Genie Luv (1 month ago)
Who makes these subtitles hahhaha I'm-
T (1 month ago)
ha anyone want to sub. im gonna fail my test and i need to make a living. thank you
James Windolf (1 month ago)
I've had nothing but good things to say about Crash Course...until today. How could you not label the 3' and 5' ends? Really?!!
William (1 month ago)
Wow, this suddenly makes a world of sense. The 5' 3' thing was hard to understand.
William (1 month ago)
Oh, because you labelled them wrong. Not hating. If anything working it out myself means I'll remember it better.
Lauren McShane (1 month ago)
Although I only watched half of it and only understood a few parts, the laying out of it combined with my other revision resources finally helped me get the gist of it - you are a star, thank you!
debjr 03 (1 month ago)
I wish you were my science teacher this has helped my some much.. my teacher just gives us very poorly made website to bearly understand DNA
Simon Oren (1 month ago)
Okazaki fragments are 100-200 nucleotides long. :)
Niko Zontini (1 month ago)
Double hel-exciting
luiza gomes (1 month ago)
This vid is so awesome Omg
Kelly Griffiths (1 month ago)
binge watching in the hope my brain takes something in for my exam tomorrow!
Nicole (1 month ago)
I’ve been watching this guy in all my 3 years in college. All my prereq classes for nursing school are of course science-based & this guy has a video on everything I swear!!! He is so smart
Maria Gu (1 month ago)
Dhruv Patel (1 month ago)
DeckZ Blaziken (1 month ago)
I'm going to assume your human no I'm a dog just kidding love you guys keep it up
Allison Bennett (1 month ago)
Where’s Rosalind Franklin? I thought she was the main contributor to this discovery...
Allison Bennett (1 month ago)
....and I watched the rest of it. Whoops
Mkmed Khaled (1 month ago)
the ad is really annoying a 12 minutes ad WTF
Wren W (1 month ago)
Bless you sir for recognizing Rosalind Franklin as the greatest
Amanda Mina (1 month ago)
" DNA can stretch to the sunn 600 times from our body...... Hey, you wanna make one?" now that is DNA replication dirty talk right there! That's​ how you get a woman
Isabella Obeshaw (1 month ago)
This is a great video. Great explanation!
corinne kokenes (1 month ago)
how dare you assume im a human
A. N. (1 month ago)
Very goad
adkat adkut (1 month ago)
he's like a smart david spade
Educator Sharmin (1 month ago)
Its really great explanation video. I like it.
LadyDragonpro 2018 (1 month ago)
who is struggling with science?! Ask Hank!! :)
Yendy Morales (2 months ago)
Who got confused in the end of the video? b/c I did 😅🤨
Hailey Trivedi (2 months ago)
Hi I have a queation. Does DNA ud=se dead DNA cells for replication
PC JOHNNY (2 months ago)
get video to 1k dislikes even i liked it
Wish I Had A Clever Name (2 months ago)
My exam is in 24 days and I want to dIE
less than 12 hours left for my exams
Kani Kani [Scarlet Wolf] (2 months ago)
Hank...you just got me s h o o k with that joke. OML. I'm telling my BIO teacher XD
Luke Paci (2 months ago)
the guy worked with USED BANDAGES! yay science! (now you know why i'm christan)
AnteConfig (2 months ago)
in the beginning of this video I saw the double helix and it kept changing the direction of spin. I love that optical illusion.
Fatima Chowdhury (2 months ago)
*DNA* Army?
Berk Karşı (2 months ago)
50% of the comments you are about to see are "Who is watching this before the exam?"
saga starr (2 months ago)
i used to binge these one day before the exam every year but... NOT THIS YEAR!!! Theres still a month to go!! Woo!!
Sean Simpson (2 months ago)
It's funny how people still talk about Rosalind Franklin being obscure and the victim of erasure, when I'm pretty sure the story of how Watson and Crick stole her work is one of the most infamous stories in science and is taught in school to children (at least in Canada).
Feng Lan (2 months ago)
Your videos get me double helixcited about Biology when I’m not very good at science.
Sambhranta Gupta (2 months ago)
Can you please explain the various types of rna:-hnrna,mrna,trna,dsrna,etc.
Michelle Forgét (2 months ago)
This entire channel honestly saves my life
Rawen Ghazi (2 months ago)
Thanks, it really helped me understand the subject. Good Work! :)
Luana Jourdan (2 months ago)
If a DNA molecule has the nucleotide sequence of A G G T C A, what is the sequence on the resulting mRNA?
cateri padilla (2 months ago)
I'm going to fail but you taught me more then my bio teacher
Harley Eileen (2 months ago)
Casually cramming for midterms
David Dong (2 months ago)
That DNA animation at the beginning of the video was amazing! You better be paying that animator a lot, you better! Unless Hank is so talented that he can do it himself with his sex...plus four fingers.
Hailey Davis (2 months ago)
i hate school >:(
Honey Bee (2 months ago)
He's like the Alton Brown of Biology! I love it! He's so cute!
lil angel (2 months ago)
this helped so much lol I have a bio test tomorrow
Justin Chen (2 months ago)
some people have down syndrome so...
Syed (3 months ago)
I want the model he is holding in his hand, if it is real.
CRAZY *TRICKS & MORE* (2 months ago)
Derik Vernon (3 months ago)
My biology teacher says for dna replication, DNA Primase adds the RNA primer. Is this true? Cause you said RNA Primase.
IQRA malik (3 months ago)
great teacher you are thank you for teaching us
chinmay patel (3 months ago)
Excellent explaination✌️✌️✌️
Black HalfnHalf (3 months ago)
The way he says "wanna make one?" comes off as so creepily sexual
CRAZY *TRICKS & MORE* (2 months ago)
I'm glad i was not the only one that was scared by thet
Buttin Muffin (3 months ago)
Christine'S Rapuza (3 months ago)
You sound like draw with jaza
Justyna Figas-Skrzypulec (3 months ago)
Thank you so much for giving Rosalind Franklin credit for her work! Watson and Crick actually acted like total sexist douchebags towards her, while stealing her results :/
You again? Hahaha. Big scishow fan here! Best teacher ever!

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